Keywords
ZBTB16::RARα
myeloid leukemia
How to Cite
Abstract
Pediatric acute myeloid leukemia (AML) is a heterogeneous disease. Advances in genetics have led to dynamic changes in the definition of specific subentities, allowing for a better understanding and treatment of this disease. Thus, the WHO's fifth classification divides AML into: AML with defining genetic abnormalities, AML defined by differentiation and myeloid sarcoma. In this paper, we describe a case of AML in a pediatric patient with complex cytogenetic alterations, whose diagnosis, classification, and treatment required interdisciplinary collaboration. A review of the current literature on the subject is also presented.
References
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