Keywords
acute leukemia, mixed phenotype, peripheral blood smear, bone marrow smear
Pediatric
How to Cite
Abstract
Acute leukemia of mixed phenotype (MPAL) is a rare group of neoplasms in which blast cells exhibit characteristics of more than one hematopoietic cell line. The term lymphoma is used when the primary lesion is located in an extramedullary site, such as a lymph node, with no or minimal evidence (<25%) of peripheral blood or bone marrow involvement. Most MPAL cases present as leukemia; therefore, several of the current diagnostic criteria in the World Health Organization (WHO) classification are difficult to apply to tissue samples. It primarily affects children and adolescents, and its diagnosis, classification, and treatment selection generate significant challenges. We report a case of a pediatric patient diagnosed with lymphoblastic lymphoma of mixed lineage, along with his treatment and evolution.
References
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