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Abstract
The purpose of oral anticoagulant therapy (OAT) is to achieve effective protection against certain thromboembolic pathologies both arterial and venous. Diseases such as atrial fibrillation or mechanical valve replacement carry a significant risk of developing thrombosis. This retrospective study was carried out on 304 determinations corresponding to 157 patients with a diagnosis of nonvalvular atrial fibrillation, pulmonary thromboembolism or deep vein thrombosis, who attended the Haemostasis and Thrombosis Department to measure their INR (international normalized ratio) for being under OAT. The objective was to compare the results of INR obtained by coagulometric method and POC method analyzing whether there are statistically significant differences between both methodologies. In addition, we evaluated if these differences generated an impact on medical decision-making. The results showed a good clinical correlation when the INR values were in normal range but when they exceeded the therapeutic range the differences were significant. We concluded that decision-making based on the results obtained by the POC method, when the upper limit of the therapeutic range was exceeded, could be different and thus affect medical decision-making.
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