Keywords
Toxoplasma Gondii
hematopoietic progenitor cell transplantation
How to Cite
Abstract
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory disorder of immune regulation. HLH following hematopoietic progenitor cell transplantation (HSCT) is unusualand the diagnosis may be challenging because diagnostic criteria overlap with common complications after HSCT, such as graft-versus-host disease and infections. We present a patient who developed HLH secondary to Toxoplasma gondii reactivation.
References
1- Komitopoulou A, Goussetis E, Oikonomopoulou C, et al. Toxoplasma gondii: How fatal is it in pediatric allogeneic bone marrow transplantation setting?. Transpl Infect Dis. 2020;22:e13226. https://doi.org/10.1111/ tid.13226.
2 - Sanchez-Petitto G, Holtzman NG, Bukhari A, et al. Toxoplasma-induced hemophagocytic lymphohistiocytosis after haploidentical allogeneic stem cell transplantation. Transpl Infect Dis. 2020;22:e13242. https ://doi.org/10.1111/tid.13242.
3 - Conrad A, Le Marechal M, Dupont D, et al. A matched case–control study of toxoplasmosis after allogeneic haematopoietic stem cell transplantation: still a devastating complication. Clinical Microbiology and Infection. May 09, 2016. https://doi.org/10.1016/j.cmi.2016.04.025.
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