Purpura fulminans secondary to Streptococcus pnemoniae infection in a patient with acquired protein S deficiency: a case report
Revista Hematología
pdf (Español (España))

Keywords

protein S deficiency
Purpura fulminans, streptococcus pneumoniae,

How to Cite

Sernaque, C., Ceresetto, J., Duboscq, C., Shanley, C., Bullorsky, E., Rabinovich, O., Palmer, S., Agustina, C., Flegler, N., Giunta, J., oliveros sandoval, karla andrea, Fernie, L., Quarchioni, M., & Stemmelin, G. (2021). Purpura fulminans secondary to Streptococcus pnemoniae infection in a patient with acquired protein S deficiency: a case report. Journal of Hematology, 24(3), 71–75. Retrieved from https://revistahematologia.com.ar/index.php/Revista/article/view/334

Abstract

Purpura fulminans is a hematological emergency characterized by cutaneous necrosis and laboratory disseminated intravascular coagulation (DIC) parameters. It can appear associated with severe infections, as an autoimmune process after benign infections in childhood or be the presenting symptom of a congenital protein C or S deficiency. A clinical case of purpura fulminans associated with acquired protein S deficiency is described in a 6-year-old patient with severe Streptococcus Pneumoniae pneumonia.

pdf (Español (España))

References

1. Hernández Blanco, R. González Montero, M.M. Urán Moreno. Post-varicella purpura fulminans: Potentially fatal. An Pediatr. 2009;70:379-82.
2. Talwal A, Kumar S, Gopal MG, Nandini As. Spectrum of purpura fulminans: report of three classical prototypes and review of management strategies. Indian J Dermatol Venereol Leprol. 2012 Mar-Apr;78(2):228.
3. Chalmers E, Cooper P, Forman K. Purpura fulminans: recognition, diagnosis and management. Arch Dis Child. 2011 Nov;96(11):1066-71.
4. GL, Darmstadt. Acute infectious purpura fulminans: pathogenesis and medical management. Pediatr Dermatol. 1998 May-Jun;15(3):169-83.
5. Gurgey A, Aytac S, Kanra G. Outcomer in children with purpura fulminans: report on 16 patients. Am J Hematol. 2005 Sep;80(1): 20-5.
6. Dogan Y, Aygun D, Yilmaz Y, Kanra G. Severe protein S deficiency associated with heterozygous factor V Leiden mutation in a child whit purpura fulminans.
Pediatr Hematol Oncol. 2003 Jan-Feb;20 (1):1-5.
7. Price VE, Ledingham DL, Krumpel A. Diagnosis and manegement of neonatal purpura fulminans. Semin Fetal Neonatal Med. 2011 Dec;1(6):318-22. 8. Nolan J, Sinclair R. Review of management of purpura fulminans and two case reports. Br J Anaesth. 2001 Apr;86(4):581-6.
9. Lalitha AV, Aruna D, Prakash A. Spectrum of purpura fulminans. Indian J Pediatr. 2009 Jan;76 (1):87-9.

All material published in the journal HEMATOLOGÍA (electronic and print version) is transferred to the Argentinean Society of Hematology. In accordance with the copyright Act (Act 11 723), a copyright transfer form will be sent to the authors of approved works, which has to be signed by all the authors before its publication. Authors should keep a copy of the original since the journal is not responsible for damages or losses of the material that was submitted. Authors should send an electronic version to the email: revista@sah.org.ar

Downloads

Download data is not yet available.