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Abstract
Adult Leukemia / Lymphoma T is an aggressive and infrequent peripheral T cell neoplasm, secondary to infection by the human T-cell lymphotropic virus type 1. This retrovirus is characterized by endemicity with a prevalence in Argentina of 5%, developing disease only 3 to 5% of infected people. The latency period is 20 to 50 years, presenting the disease in adults. The virus leads to the clonal transformation of CD4 T lymphocytes, giving rise to different subtypes of disease ranging from indolent to more aggressive forms. The association of this pathology with paraneoplastic phenomena and with infectious complications derived from immunosuppression is frequent. Due to its low prevalence constitutes a diagnostic challenge in daily practice, we present a case of a 53-year-old man from the Argentine Northeast who was diagnosed with acute T leukemia associated HTLV1 infection, associated with hypercalcemia and disseminated cryptococcosis, presenting by morphology a unusual variant Sezary like
References
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