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Abstract
The hematopoietic system is an organ with particular characteristics, with the capacity to self-renew and differentiate itself, guaranteeing a constant number of precursors and the production of all the blood cells throughout an individual´s life. The differentiation to the different cell profiles will depend on the activation stimulies generated and the selective expression of surface receptors which allow the mobilization of cells from the bone marrow towards the effectors sites. The continuous stimulation of hematopoietic cells may be harmful for them, contributing in the development of oncological or autoimmune diseases. The discovery of the SURVIVIN protein provides the opportunity for the investigation of a potential therapeutic target for the apoptosis modulation of these deregulated cells.
All material published in the journal HEMATOLOGÍA (electronic and print version) is transferred to the Argentinean Society of Hematology. In accordance with the copyright Act (Act 11 723), a copyright transfer form will be sent to the authors of approved works, which has to be signed by all the authors before its publication. Authors should keep a copy of the original since the journal is not responsible for damages or losses of the material that was submitted. Authors should send an electronic version to the email: revista@sah.org.ar